Human Biospecimen Repository
Cureline procures, ships, stores, analyses and distributs thousands of human specimens every year. Our major biorepository is located in the United States and high-quality human specimens are immediately available to our clients and collaborators.
Bioethical Policies and Clinical Information
Our team collaborates with the major clinical and research centers in Europe, Asia, and the USA on developing collection protocols that are approved by local IRBs and Ethical Committees and that comply with international and local regulations and guidelines.
A standard patient consent form is used for all Standard Collection Protocols. Project-based consent forms are developed for each custom study in collaboration with clinical sites and the study sponsor. Standard Operating Procedures (SOPs) are implemented to guard patient’s rights and to use the samples with maximum efficiency.
All human materials provided by Cureline are properly consented, de-identified and selected with accurate clinical diagnosis and therapy regimens by certified medical professionals. Standard clinical information provided for each case includes age, gender, diagnosis, a pathology report summary and treatment history.
If requested, a custom clinical report form (CRF) is developed and implemented in prospective procurement studies. A detailed pathology report from a US-board certified medical pathologist and H&E slides can also be provided upon request
Quality:
Our standard procurement protocols accommodate the quality requirements of most research methods used in the drug discovery and development process. Cureline guarantees the quality of all provided human materials and services.
- Frozen Tissues FF tissues: Oncology, Inflammation, Neurological Diseases, Normal Tissues
- FFPE Blocks FFPE tissues (Oncology, Inflammation, Neurological Diseases, Normal Tissues)
- Blood and Bone Marrow Human specimens from patients with leukemia, multiple myeloma, MDS, etc.
- Cell Fractions Primary human viable cells and marker-specific cellular subfractions for functional studies and expression analysis
- Primary Cell Lines Primary cells cultures from solid tumors, cancer blooc, cancer bone marrow and normal tissues (custom protocols and available products)
- Biospecimen Sets Comprehensive human specimen sets from patients with solid tumors, hematologic malignancies, rheumatoid arthritis, endometriosis. Normal human issue panels.
- Treatment-Relevant Serum Collection of treatment-relevant cancer serum with clinical outcome data
- Human Therapeutic Plasma Cureline provides human therapeutic plasma for diagnostics development and validation.
