Custom Human Tissue Acquisition

Cureline offers to the biopharmaceutical and diagnostics companies collection, preservation and processing of clinically-defined and consented human tissues for research.  We have standard and custom tissue procurement protocols available for your research programs.

Our human tissue procurement protocols accommodate the quality recruitments for research applications used in the drug discovery and development process, including :

 •    Target Validation

     Expression Profiling

     Genotyping

 •    Preclinical Modeling

     Molecular Diagnostics

     Drug Safety Evaluation

     Biomarker Discovery and Validation

     Clinical Assay Development


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Bioethical Policies

Cureline collaborates with major clinical and research centers in Europe, Asia, and the USA on human specimen acquisition projects.  Our team develops standard and custom tissue procurement protocols that are approved by local IRB and Ethical Committees and that comply with international and local regulations and guidelines.  

Cureline is committed to ensuring that the collection of human specimens for research purposes does not interfere with the patient's well-being, and that a proper consent form is developed for each study in collaboration with clinical sites and the study sponsor.  Standard Operating Procedures (SOPs) are implemented to guard patient’s rights and to use the human specimens with maximum efficiency.

Clinical Information

All human specimens provided by Cureline are properly consented, de-identified and selected with accurate clinical diagnosis and therapy regimen by certified medical professionals.  Standard clinical information for each case includes age, gender, diagnosis, pathology report summary and treatment history.  Follow-up is available upon request.

If requested, a custom clinical report form (CRF) is developed and implemented in prospective procurement studies.  A detailed pathology report from a US-board certified medical pathologist and H&E slides can also be provided upon request.

Solid Tumor Oncology

Collection of human tumor specimens from patietns with solid tumors

Hematologic Malignancies

Human biospecimens from patietns with Hematologic Malignancies (ALL, AML, CLL, CML, MM, MDS, etc.)

Inflammation

Inflammation (Rheumatoid Arthritis, Lupus, Asthma, Cron’s Disease, Psoriasis, etc)

Neurological Diseases

Human specimens from patients with neurological conditions (Parkinson’s Disease, Alzheimer Disease, Multiple Sclerosis)

Normal Tissues

Normal human tissue sets available for cross-reactivity studies

Other Indications

Cardiovascular diseases, metabolic disorders, endometriosis, dermatology, inherited diseases